Creator:

Polański, Andrzej ; Kimmel, Marek

Contributor:

Kimmel, Marek - red. ; Lachowicz, Mirosław - red. ; Świerniak, Andrzej - red.

Title:

Population genetics models for the statistics of DNA samples under different demographic scenarios - Maximum likelihood versus approximate methods

Subtitle:

Cancer Growth and Progression, Mathematical Problems and Computer Simulations

Group publication title:

AMCS, volume 13 (2003)

Subject and Keywords:

DNA samples ; demography ; coalescence

Abstract:

The paper reviews the basic mathematical methodology of modeling neutral genetic evolution, including the statistics of the Fisher-Wright process, models of mutation and the coalescence method under various demographic scenarios. The basic approach is the use of maximum likelihood techniques. However, due to computational problems, intuitive or approximate methods are also of great importance.

Publisher:

Zielona Góra: Uniwersytet Zielonogórski

Date:

2003

Resource Type:

artykuł

Pages:

347-355

Source:

AMCS, volume 13, number 3 (2003) ; click here to follow the link

Language:

eng

Rights:

Biblioteka Uniwersytetu Zielonogórskiego